As PCS74 mentioned, the "principles of engine operation" don't change. BUT... there are different effects from the same principles involved in a turbo engine and an engine without a turbine in the exhaust system, either supercharged or normally aspirated. In the turbo engine there is little or no "ram effect" which can actually pull the gasses out of the cylinder. The turbine, when it is working, will always require pressure in the exhaust system, so the scavenging effect will be minimal, if any. In addition, the requirement of combining the exhaust from all cylinders and running to a turbine inlet makes it almost impossible to get "equal length" tubes, for tuning. Of course, if you put the turbo in the trunk, like that Camaro set-up.. but that's not a Buick! For a race engine, running in a narrow power band, you can set up the turbo to operate with less back pressure, and then the "tuned headers" will be more useful, as Bruce mentioned. But a turbo set up that way will have a lot of lag, and be a pain to drive on the street. Bottom line.. what Bruce said. There are better things to spend your money on.