No i wouldnt drop anytiming, i may even add a degree or 2.
With a single turbo running 30+s pounds i run around 26* on most car i tune(on C-16 of course)
As far as ayour A/F i would set it around 10.5 to start and once it runs clean there take it back to 11-1 or so
Make sure to add a few % to the VE tables also in the upper ranges
HTH