#1 choice for head shots on whitetail doe, axis doe, and feral hogs - Remington Model 700 BDL with target crowned barrel in cal. 22-250 with Winchester 45-grain JHP Varmint loads. You either hit 'em and turn their lights off, or miss completely. It has never missed in my hands (knock on wood). Fresh from the box this rifle shot 3/4" groups at 200 yards. Very smooth shooting gun and any gunsmith worth his salt can get the trigger to a 1-1/2# pull with their eyes closed. Remington 700's are a joy to shoot, and the .22-250 can be shot all day long. Great for youngsters as well - I've had 10-year olds shoot this rifle and want to continue all day long with a little padding on the butt stock; it's truly a confidence builder for them since it's so accurate.
#1 choice for whitetail bucks and #2 choice for hogs - Weatherby Vanguard Sub-MOA with target crowned barrel in cal. 7mm Rem. Mag. Absolutely deadly to 375-yards (my longest kill shot). I have missed with this rifle several times due to its ferocity and horrendous factory trigger. Since I installed the 2# Timney trigger group two years ago, nothing but good news from it.
Next on the list will be something in between these two as far as knock-down power. Considering a .257 Roberts, 7mm-08, or the good ol' .308 Win. Undecided at this point.
Good thread - I love hearing what others use to hunt with!!!!