E85 will require larger injectors and anything larger than 80# will be low Z . Unless you spend big money for +80# high Z injectors and Cal does sell them also .
I am still using stock ecm. I have a fresh buildt motor and I would love to have a fast street car. I don't plan on racing anytime soon. I've have s ok me bad ecms. I would like to learn more about tuning.
I ran the sportsman on e85 for a couple years. I liked it a lot. Learned the tuning side of it, which I wanted to know. It’s pretty straight forward. I know enough to get by but am still learning as I tune the car more. I upgraded to the xfi2.0 for more fine tuning. Largest most readily available injectors for high z injectors are the 80s but I have 160s cost a bit though. 80s are sufficient along with the dw300 but if you want to fast you’ll need to step your setup up. With the 80s I was 70/80% duty cycles and I had a 450 pump which were at about 350lph. Of course I had bigger fuel lines.
You can go real fast on a stock ecm , you will need it modded for low Z injectors , then get low Z 120's & chip from Eric. Works for me , I'm at 10.30's @ 129 .