I run the same TE45a I've had since 2004. Not touched at all. Been through 3 builds with it. Currently 255? inch stroker, alum heads, and I love the Holley EFI. I got to ditch all the piggyback wiring and used a new Cruz performance engine harness for the Buick and Holley. Holley coils, no more coil pack module madness, no waste spark, no MAF, easy to tune, one system to log and do everything. I'll never go back stock.
On your setup, the 45a and a 210/210 cam I went 10's at 127 all day long on irons with just a bowl port with the 45a. I run a 3600 stall PTC 9.5 NLU, it really stalls at 3100-3150 at 0 boost. I'll probably not go back to a lockup unless its one of them ninja ones for pro mod type big dog cars I've seen on Stevie Jackson's channel.