I don't know what everyone's infatuation with O/L tuning is, but I know it's big on other platforms like LS's that require it more.
I'm trying to remember what has been done regarding AFR settings to make the PCM happy with E85. There may be some guys on GrandPrixForums who have more info. Here's a discussion they pinned there...
http://www.grandprixforums.com/pcm-tuning/94283-the-defacto-guide-to-tuning-your-car-for-e85.html
Typically, I just use the MAF table to fine tune, one all the AFR settings in PE are where I want them, and the Injector table is how it needs to be. I may get fancy, depending on how much free time I have after the engine's running, to do a VE tune for O/L... TBD.